CR 13426:1998

Biotechnology - Microorganisms - Report on the criteria used to classify Group I genetically modified microorganisms CR 13426:1998

Publication date:   Jun 11, 2004

General information

99.60 Withdrawal effective   Jun 17, 2020


CEN/TC 233 Biotechnology

CEN Report

07.080   Biology. Botany. Zoology | 07.100.01   Microbiology in general



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This CEN Report reviews the safety criteria for hosts, vectors, inserts and genetically modified microorganisms (GMM’s) used by the competent authorities of Member States of the European Union to classify GMM's as intrinsically safe, i.e. as Group I GMM’s. The report may assist both users and regulatory authorities in classifying GMM’s, including mammalian and plant cells, as safe for human health and the environment.

This CEN Report covers Group I GMM’s that are applied in research and development activities and those applied in industrial applications, which are frequently activities on a larger scale. Although most of the information available relates to GMM’s that are to be used for research and development, the safety criteria for GMM’s to be used for the latter kind of activities show much overlap. No listings of hosts and vectors are given, because such lists are readily available and are inevitably incomplete due to the continuous addition of newly classified biological agents.

Related legislation

Legislation related to this standard


Deliberate release into the environment of genetically modified organisms


Contained use of genetically modified micro-organisms


Protection of workers from risks related to exposure to biological agents at work

Life cycle


CR 13426:1998
99.60 Withdrawal effective
Jun 17, 2020