ISO 12243:2003

Medical gloves made from natural rubber latex — Determination of water-extractable protein using the modified Lowry method ISO 12243:2003

Publication date:   Sep 23, 2003

General information

90.93 Standard confirmed   Sep 12, 2023


ISO/TC 45/SC 3 Raw materials (including latex) for use in the rubber industry

International Standard

83.040.10   Latex and raw rubber



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ISO 12243:2003 specifies a method for the determination of the amount of water-extractable protein in natural rubber (NR) gloves for medical use. The method is potentially suitable for the determination of extractable protein in other articles made from NR latex; however the extraction procedures and times have not been validated and will vary with the type of article to be tested. Other methods for the determination of specific proteins in medical gloves exist (these are described in an annex) but they are not of general applicability.
This International Standard is concerned solely with the method of assay. It is not concerned with sampling nor does it purport to address the safety implications of the values obtained or requirements for labelling.

Life cycle


ISO 12243:2003
90.93 Standard confirmed
Sep 12, 2023


ISO 12243:2003/Amd 1:2012