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ISO 21766:2021

Tobacco and tobacco products — Determination of tobacco-specific nitrosamines in tobacco products — Method using LC-MS/MS ISO 21766:2021

Publication date:   Feb 3, 2021

General information

90.93   Standard confirmed   Jun 5, 2026

ISO

ISO/TC 126 Tobacco and tobacco products

International Standard

65.160   Tobacco, tobacco products and related equipment

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Published

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Scope

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in tobacco and the following tobacco products: cigarettes, cigars and smokeless tobacco products using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The TSNAs determined with this method are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Life cycle

PREVIOUSLY

WITHDRAWN
ISO 21766:2018

NOW

PUBLISHED
ISO 21766:2021
90.93 Standard confirmed
Jun 5, 2026




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