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ISO 19290:2021

Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS

Publication date:   Feb 3, 2021

General information

60.60 Standard published   Feb 3, 2021

ISO

ISO/TC 126 Tobacco and tobacco products

International Standard

65.160   Tobacco, tobacco products and related equipment

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Scope

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Life cycle

PREVIOUSLY

WITHDRAWN
ISO 19290:2016

NOW

PUBLISHED
ISO 19290:2021
60.60 Standard published
Feb 3, 2021