ISO 10993-4:2017

Biological evaluation of medical devices — Part 4: Selection of tests for interactions with blood

Publication date:   Apr 12, 2017

General information

90.92 Standard to be revised   Oct 29, 2024

ISO

ISO/TC 194 Biological and clinical evaluation of medical devices

International Standard

11.100.20   Biological evaluation of medical devices

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Scope

ISO 10993-4:2017 specifies general requirements for evaluating the interactions of medical devices with blood.
It describes
a) a classification of medical devices that are intended for use in contact with blood, based on the intended use and duration of contact as defined in ISO 10993‑1,
b) the fundamental principles governing the evaluation of the interaction of devices with blood,
c) the rationale for structured selection of tests according to specific categories, together with the principles and scientific basis of these tests.
Detailed requirements for testing cannot be specified because of limitations in the knowledge and precision of tests for evaluating interactions of devices with blood. This document describes biological evaluation in general terms and may not necessarily provide sufficient guidance for test methods for a specific device.
The changes in this document do not indicate that testing conducted according to prior versions of this document is invalid. For marketed devices with a history of safe clinical use, additional testing according to this revision is not recommended.

Life cycle

PREVIOUSLY

WITHDRAWN
ISO 10993-4:2002

WITHDRAWN
ISO 10993-4:2002/Amd 1:2006

NOW

PUBLISHED
ISO 10993-4:2017
90.92 Standard to be revised
Oct 29, 2024

CORRIGENDA / AMENDMENTS

IN_DEVELOPMENT
ISO 10993-4:2017/PRF Amd 1

REVISED BY

IN_DEVELOPMENT
ISO/AWI 10993-4