ISO 17099:2014

Radiological protection — Performance criteria for laboratories using the cytokinesis block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry

Publication date:   Nov 6, 2014

General information

90.92 Standard to be revised   Oct 29, 2021

ISO

ISO/TC 85/SC 2 Radiological protection

International Standard

13.280   Radiation protection

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Scope

ISO 17099:2014 addresses the following:
a) confidentiality of personal information for the customer and the laboratory;
b) laboratory safety requirements;
c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;
d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;
e) scoring criteria;
f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;
g) reporting of results;
h) quality assurance and quality control;
i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.

Life cycle

NOW

PUBLISHED
ISO 17099:2014
90.92 Standard to be revised
Oct 29, 2021

REVISED BY

IN_DEVELOPMENT
ISO/AWI 17099