EN 16274:2021

Method for analysis of allergens - Quantification of an extended list of 57 suspected allergens in ready to inject fragrance materials by gas chromatography mass spectrometry

Publication date:   Sep 16, 2021

General information

60.60 Standard published   May 5, 2021


CEN/TC 347 Methods for analysis of allergens

European Norm

71.100.60   Essential oils



Language in which you want to receive the document.


The present method permits the identification and quantification of the volatile compounds suspected as allergens, which are present in the fragrance compounds and fragrance raw materials used in cosmetic products. The analysis is performed by gas chromatography and mass spectrometry (GC-MS) on matrix samples which are "ready to be injected" and which are compatible with gas chromatography.
The analytes covered by this procedure are based on the contents of Tables 13.1 and 13.2 in the SCCS 1459/11 opinion document (1) and as listed in the legislation proposed by the European Commission. The rationale behind the final choice of procedure analytes is given in the table found in Annex J.
The method was validated at IFRA and CEN level.

Life cycle


EN 16274:2012


EN 16274:2021
60.60 Standard published
May 5, 2021