EN ISO 17099:2017

Radiological protection - Performance criteria for laboratories using the cytokinesis block micronucleus (CBMN) assay in peripheral blood lymphocytes for biological dosimetry (ISO 17099:2014)

Publication date:   May 17, 2018

General information

60.60 Standard published   Oct 11, 2017


CEN/TC 430 Nuclear energy, nuclear technologies, and radiological protection

European Norm

13.280   Radiation protection



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ISO 17099:2014 addresses the following:
a) confidentiality of personal information for the customer and the laboratory;
b) laboratory safety requirements;
c) radiation sources, dose rates, and ranges used for establishing the calibration reference dose-effect curves allowing the dose estimation from CBMN assay yields and the minimum resolvable dose;
d) performance of blood collection, culturing, harvesting, and sample preparation for CBMN assay scoring;
e) scoring criteria;
f) conversion of micronucleus frequency in binucleated cells into an estimate of absorbed dose;
g) reporting of results;
h) quality assurance and quality control;
i) informative annexes containing examples of a questionnaire, instructions for customers, a microscope scoring data sheet, a sample report and advice on strengths and limitations of current automated systems for automated micronucleus scoring.

Life cycle


EN ISO 17099:2017
60.60 Standard published
Oct 11, 2017


prEN ISO 17099 rev


Adopted from ISO 17099:2014 IDENTICAL